While research and product development teams want to investigate and prove out every concept and potential outcome, they need to reduce the chance of unanticipated negative effects. Computational modeling and simulation (CM&S) lets you create and simulate human biologic test environments and conditions to complement the validation of safety and effectiveness by nonphysical means.
The Living Heart Project has brought together a multidisciplinary team of experts to collaborate on breakthrough technology for improved products and treatments for cardiovascular disease. The project’s first output is the Living Heart Model (LHM), a realistic 3D computational model of the human heart. This case study discusses the Living Heart Project and the plans for further developments and clinical applications rising from its efforts.
Understanding the blood flow dynamics (hemodynamics) and the fluid forces exerted on the blood by implantable medical devices and predicting blood damage are intricate parts of interventional medical device design. This article aims to assess the performance of Abaqus/CFD in modeling hemodynamics using the FDA Benchmark Nozzle model.
The Living Heart Human Model provides a unique testing environment where a stent can be deployed virtually in coronary arteries and deformed mechanically during the cardiac cycle. Once the mechanical deformation results are obtained, the long-term durability of the stent can be assessed. The virtual nature of the test provides a physiologically accurate methodology to test new and existing devices without exposing patients to unnecessary risk.
Medical device developers use realistic simulation solutions to accelerate the overall product innovation process, reducing development costs and improving patient safety and product quality. Simulation solutions allow medical device companies to more efficiently evaluate design alternatives, accelerate long-term stress life testing to predict product reliability, collaborate on projects, and leverage computing resources for more efficient design analysis.