Benefits Of Using Octet® BLI Systems In IVD Product Development

By Shuo Liang, Hasret Altan-Martin, Christin Ronsör, David Apiyo

One of the most common immunoassay formats for in vitro diagnostics (IVD) is the lateral flow assay (LFA). Antibodies play a crucial role, as their quality attributes and interaction with antigens directly impact the test performance of LFAs. For the development and optimization of LFAs, it is essential to understand the interaction between antibodies and antigens as well as antibody quality.

The Octet® system is a powerful and easy-to-use high-throughput solution designed for analyzing antibody-antigen interactions. This system is based on bio-layer interferometry (BLI) technology, which enables the real-time, label-free monitoring of biomolecular interactions. Discover how Octet® systems can be utilized during the quality control, assay development, and assay optimization stages in the product development of LFAs.