We’ve all seen or heard commercials from the American Stroke Association (ASA) encouraging people who suspect they might be having a stroke to call 9-1-1 right away, because “time lost is brain lost.”. Stroke is the No. 5 cause of death in the United States, killing nearly 130,000 people a year. That’s one in every 20 deaths, according to the ASA. But even if you survive a stroke, you are not even close to being out of the woods.
Before he was an “Outdoor Man” marketing sporting goods in the Rocky Mountains as the Last Man Standing, Tim (“The Tool Man”) Taylor did most of his work indoors — on a little show called Home Improvement. Fortunately for the often accident-prone know-it-all, he had a competent sidekick in the mild-mannered Al Borland, who often knew a better way to get things done properly.
When incorporating human factors into medical device development, conducting user testing and gathering feedback from the device’s target end users is critical. To do this properly, the end user groups must be appropriately defined.
Because of its sensitivity to thermal degradation, PLA is difficult to recycle and actually becomes a contaminant in the plastics stream of municipal solid waste. Using the newly discovered process, different grades of PLA can be removed from a stream of commingled plastics and broken down to give high value chemicals. Some of these chemicals, called monomers, can be purified and used as feedstock to synthesize virgin PLA resin.
CAD is the leading cause of death in the United States in both men and women. Treating CAD with bioresorbable vascular scaffolds (BRS) is considered by many to be the “next revolution” in endovascular therapy. This white paper presents the basics of BRS technology, its processing and manufacturing challenges, and its advantages in use with polymer technologies.
Product engineers at catheter manufacturing companies will be only too aware of the problem of delamination – the separation of material layers within the catheter. The solution lay in the design of an additional material layer between the inner etched PTFE liner and the outer jacket material of the catheter. This extra layer would deliver the crucial adhesion required to prevent delamination, ideally without increasing the outer diameter of the finished catheter.
Polyimides (PIs) occupy a particular place in commercial plastics because of their ability to tolerate and function in extremely high temperatures. They are also well known for other beneficial properties including insulating capability, chemical resistance, and excellent mechanical attributes. With their combination of properties and their ability to be tailored toward application specifics, polyimides offer some of best options for performance in high heat and other difficult environments. This white paper provides a brief overview of polymide properties, their structure, and how they are synthesized for use in extreme environment applications.
Have you ever looked closely at an object and thought about how it's made? What are all the steps involved in creating the item from initial design to final production? Maybe you would like to take on the task of getting a product manufactured. There are many aspects to the process of creating a wide variety of products, but they all have something in common at the beginning. You will need to understand this common element because it's the key to a successful design.
Medical device design and development is the cyclical process of creating a device for a specific task or set of tasks, and then continuously reevaluating its effectiveness and improving upon it until the device reaches obsolescence. Design and development begins with ideation and the creation of a concept that, if found to be both fiscally and clinically viable, is then designed, engineered, and prototyped. This preclinical period includes bench testing — accomplished through simulated use of the product — and animal testing, along with any necessary redesign work.
Throughout the process, the proposed medical device, and the process by which it will be manufactured, is examined for flaws that may negatively impact the device’s safety, market viability, regulatory acceptance, customer satisfaction, usability, or profitability. Any shortcomings are corrected, and the improvements applied to the final design. Due to the wireless connectivity capabilities of many modern medical devices, cybersecurity and interoperability also must be incorporated into the design. Clinical testing is conducted, using human subjects, to further expose flaws and confirm product strengths. Once both the product design and the manufacturing process have been validated and approved by the U.S. Food and Drug Administration (FDA), production and commercialization of a device may begin.
Each year, nearly 800,000 people in the U.S. experience a stroke, and almost 90 percent of those are ischemic strokes in which a clot cuts off blood flow to part of the brain. To prevent further injury, blood flow to the brain must be restored as quickly as possible.
Empatica Inc has received clearance from the FDA for Embrace, its award-winning smart watch. Embrace uses AI (advanced machine learning) to monitor for the most dangerous kinds of seizures, known as "grand mal" or "generalized tonic-clonic" seizures, and send an alert to summon caregivers' help.
For the first time, researchers have fabricated sensing elements known as fiber Bragg gratings inside optical fibers designed to dissolve completely inside the body.
A team of scientists from the National University of Singapore (NUS) has developed a way to wirelessly deliver light into deep regions of the body to activate light-sensitive drugs for photodynamic therapy (PDT).
Extremely fine porous structures with tiny holes - resembling a kind of sponge at nano level - can be generated in semiconductors.
Tyndall and Sanmina Corporation have announced a research collaboration, which will focus on the development of a novel wireless technology for a commercial wrist-worn health-monitoring platform.
When studying diseases or testing potential drug therapies, researchers usually turn to cultured cells on Petri dishes or experiments with lab animals, but recently, researchers have been developing a different approach: small, organ-on-a-chip devices that mimic the functions of human organs, serving as potentially cheaper and more effective tools.
Cells communicate with each other through a number of different mechanisms. Some of these mechanisms are well-known: in animals, for example, predatory threats can drive the release of norepinephrine, a hormone that travels through the bloodstream and triggers heart and muscle cells to initiate a "fight-or-flight" response.
Each year 40,000 babies in the U.S. are born with a congenital heart defect, often caused by a defective heart valve, which is estimated to account for 8,000 to 13,000 new cases in the U.S. alone.
A team of researchers at DGIST has recently developed a technology which enables to acquire a high resolution mass spectrometry imaging in micrometer size of live biological samples without chemical pretreatment in the general atmospheric pressure environment.