03.21.23 -- Cleaning Validation Strategies And The Benefits Of Aqueous Cleaning

Getting the best results from any cleaner requires proper mixing and cleaning procedures. Understanding the testing methods commonly used for determining cleanliness of pharmaceutical processing equipment is also important. Explore mixing directions for aqueous cleaning detergent as well as methods for monitoring performance.

Virtually any pharmaceutical manufacturing equipment — from tablet presses to stainless-steel mixing tanks — can be cleaned to stringent critically clean criteria through aqueous cleaning. Learn how aqueous cleaning in pharmaceutical manufacturing can provide a number of benefits in terms of efficacy, minimal surface contact, reduced residue potential, and easier cleaning validation.

In a cleanroom environment, it is critical to avoid the creation of powdered clouds. Additionally, detergents used in cleaning should allow for an easy rinse and have sufficient detergent capacity for the highly controlled and clean classified space. Read more about how liquid concentrate detergents are useful in these environments.

A faster and more efficient method to remove silicone grease from syringes is to use very hot water for cleaning and very hot water for rinsing. Discover the ideal water temperatures for cleaning and rinsing, the benefits of using hot water for this process, and other concerns.

Cleaning validation or verification is a necessary regulatory compliance step in medical device manufacturing and reprocessing. Support from the cleaner manufacturer can save time and money when establishing cleaning validation or verification processes. Learn the basics of cleaning validation, ways cleaner manufacturers can simplify and accelerate the process, and more.

Today's aqueous critical-cleaning detergents are blended for specific applications. Substrate, degree of soil load, and cleaning processes are all important considerations when selecting a detergent. Explore several key questions to ask about a detergent brand to ensure that it meets your specific cleaning need.