White Paper

Frangible Seal Reagent Blisters Deliver Precision Performance To Point-Of-Care Diagnostic Testing

By Blake S. Perkins, Executive Director, Diagnostic Business Development, J-Pac Medical, LLC

Frangible seal reagent blisters, Point-of-Care (POC) diagnostic testing, In Vitro Diagnostic (IVD) testing, medical diagnostics, precision diagnostics testing, unit-of-measure dispensing, custom blister reservoirs, diagnostics manufacturing.

The continuing growth of Point-of-Care (POC) In Vitro Diagnostic (IVD) testing is supported by technology improvements and the recognition that rapid test results offer economic and patient outcome benefits. The integration of frangible seal reagent blisters into various technology platforms holds promise for more precise and reproducible results compared to currently accepted methods – an important consideration for any end-user. This paper examines the uniform processing and performance of J-Pac Medical’s frangible seal Safe Seal™ blisters and compares burst seal strength and dispensing performance versus a conventional eyedropper method. To demonstrate J-Pac Medical’s process control over given material sets, a single blister design was created with commercially available foil materials, filled and then sealed using different processing parameters.

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