Article | May 20, 2019

Improving Microscopy And Biological Imaging With Backside Illuminated (BI) sCMOS Sensors

Source: PCO-TECH Inc.

By Scott Metzler, PhD, OEM Business Development Manager, PCO America

DNA-PAINT imaging in a cellular environment. Microtubules are labeled with alpha tubulin primary antibodies and DNA-conjugated secondary antibodies. Imaging was performed in TIRF mode with an un-cooled sCMOS camera (pco.panda 4.2). (Courtesy of M. Auer, T. Schlichthaerle and R. Jungmann, Max-Planck-Institute of Biochemistry, Munich, Germany)

Biological labs can get better and more quantifiable image data from microscopes with sCMOS sensor-based devices.