Guest Column | April 9, 2025

Unlocking The Potential Of Sensor-Based Digital Health Technologies For Mental Health Conditions

By Lucy Cesnakova, program lead, Digital Medicine Society

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As mental health disorders continue to climb globally — now affecting nearly 1 billion people — the need for earlier detection, continuous monitoring, and more personalized interventions is more urgent than ever. Sensor-based digital health technologies (sDHTs), including wearables and embedded sensors, are emerging as a transformative force in the management of mental health conditions like anxiety, depression, and psychosis.

To work toward this future state, a collaboration of clinicians, researchers, technologists, and people with lived experience conducted research and released a report that outlines a framework for advancing sDHTs in both clinical research and practice. The report emphasizes that while these technologies are not a panacea, they offer opportunities to shift mental healthcare from reactive to proactive.

The Potential Of Sensor-Driven Monitoring

Sensor technologies are capable of capturing continuous behavioral and physiological data to offer real-time, context-rich insights into a person’s mental state, which have traditionally been difficult to quantify objectively.

For example:

  • Sleep disruptions, often an early sign of depression or anxiety, can be tracked with actigraphy, smartwatches, or contactless radar sensors.
  • Social withdrawal, a hallmark of psychosis or depression, can be inferred from GPS movement patterns, call/text frequency, and Bluetooth proximity data.
  • Heart rate variability (HRV) and respiration changes, indicators of autonomic nervous system dysfunction, are linked to anxiety and can be monitored via PPG and ECG sensors.
  • Speech and language features, captured via smartphone microphones and analyzed through natural language processing (NLP), are a huge area of interest for predicting mood shifts and psychotic episodes.

Insights derived from these measures, once validated, have the potential to inform timely clinical decisions and even deliver just-in-time interventions.

Fit-For-Purpose: Not Just Any Sensor Will Do

One of the central takeaways of the report is the need for mental health-specific validation of the available technologies. Most sDHTs were not developed with psychiatric use in mind, and retrofitting general-purpose fitness trackers for clinical diagnostics requires careful design considerations.

On top of validation, device usability is paramount for mental health applications. For example, individuals with depression may lack motivation to interact with a complex device, or psychosis patients may experience paranoia if devices are obtrusive or unfamiliar. In anxiety disorders, ill-timed alerts could exacerbate symptoms. Therefore, the design must adapt to the target population — in these example cases with simplicity, discretion, and offline capability or long battery life.

Robust sensor and algorithm performance is equally critical. Devices must operate reliably across different populations and environments, over long periods of time, and their algorithms need validation within the target clinical context. Large-scale studies can provide opportunity for such validation, as well as longitudinal data collection for further improvement of the algorithm or model performance.

Digital Devices In Clinical Research And Care Of Mental Health

Despite promising developments, the deployment of sDHTs at scale remains limited due to:

  • high costs and low access to the sensor-based technologies
  • limited digital literacy among users and clinicians
  • privacy concerns, especially with sensitive data like geolocation or audio
  • insufficient clinical validation in real-world populations.

Addressing these challenges requires a holistic strategy. Subsidizing device access, expanding digital literacy programs, and involving patients in co-design can improve adoption. Developers must follow strict data privacy standards and comply with regulations like GDPR and HIPAA, particularly as mental health data is highly sensitive and often stigmatized.

Sensor-Based Technologies Of The Future

Smartphones and wristband wearables, which often incorporate multiple sensor modalities, provide a fast adoption pathway in mental health populations due to their ubiquity. Apart from these, new form factors such as chest patches and contactless sensors will likely open new applications in mental health.

The three priorities for the development of the new sensors and devices are:

  1. Integrate well-established sensors in unobtrusive form factors (such as wristbands and rings) for multimodal data collection.
  2. Establish that existing algorithms generating insights into sleep, physical activity, and other relevant aspects of mental health are performing as expected in mental health populations and can be further refined and improved.
  3. Develop novel and more advanced sensors, including entirely new sensor modalities that can capture subtle behavioral cues or biochemical components.

Whether building or refining sensor-based digital health tools, it’s crucial to keep things as effortless as possible for users. That means focusing on passive data collection, discreet and comfortable designs, long battery life, and improvement of algorithms that actually deliver meaningful insights for mental health research and care.

The road ahead for sensor-driven mental healthcare is complex but promising. It requires sustained investment, ethical foresight, and, above all, patient-centered design. As the report makes clear, the question is no longer if these technologies will shape the future of mental healthcare but how we’ll ensure they do so responsibly, equitably, and effectively. The next chapter of mental health innovation is already unfolding and will be powered by sensors, data, and a renewed focus on the human experience.

About The Author:

Lucy Cesnakova is a program lead at the Digital Medicine Society (DiMe) where she has led projects in digital measurements and health technologies: a flagship pre-competitive collaboration to advance the digital measurement of nocturnal scratch, an initiative that explores the path forward for sensor-based digital health technologies for mental health, and work on using patient-generated health data in development of medical products and health technologies. She works with industry, patient organizations, regulators, clinicians, and payers to create resources to improve adoption of digital technologies in research and care. Previously, Cesnakova led technical development of digital endpoints and other software solutions as a product lead.