Mesa Labs Articles

  1. How To Prove A Sterility Assurance Level Of 10⁻⁶ 2/13/2024

    Explore the Biological Indicator/Bioburden (BI/BB) method for achieving sterilization of products along with the prerequisite studies needed to develop the sterilization process.

  2. 6 Reasons To Use Biological Indicators During Your Sterilization Cycle 2/13/2024

    Understand the importance of biological indicators, and learn why they should be integral to any comprehensive sterilization program.

  3. Annex 1 Compliance Guidelines For Biological Indicator Users 6/26/2023

    Gain a deeper understanding of the requirements, guidelines, and best practices for Annex 1 compliance whether you're in pharmaceuticals, healthcare, or any field utilizing biological indicators.

  4. Caramelization Of LSBIs Due To Extended Thermal Insult 6/6/2023

    Learn about liquid submersible biological indicators (LSBI), including the three basic LSBI formats, and how caramelization due to long sterilization cycles affects the media's ability to promote spore growth.

  5. Product D-Value Study - Part 2, Heat-Sensitive And Atypical Aqueous Liquids 10/5/2022

    How can your organization use this critical tool when developing your sterilization process for heat-sensitive products and low F0 cycles?

  6. Why Perform A Product D-Value Study? 10/5/2022

    Follow a discussion on non-heat sensitive aqueous liquid product sterilization and the use of the Overkill method and Bioburden/BI method.

  7. Product D-Value Studies: A Critical Tool In Sterilization Process Development 10/5/2022

    Learn about what questions to ask when developing a sterilization method and a critical tool that can help guide your decisions.

  8. Biological Indicators And The European Pharmacopoeia 5/10/2022

    Here, we review the information concerning biological indicators in European Pharmacopoeia General Chapter 5.1.2, which is more detailed and covers a wider scope than the previous version.

  9. Why Biological Indicators Survive A Validated Cycle 5/10/2022

    We review what to do should you ever find yourself in the situation where the probes indicate conditions that would render killed BIs, yet the units are testing positive.

  10. Biological Indicators For Vapor Hydrogen Peroxide Isolator Decontamination 4/20/2022

    We highlight vapor hydrogen peroxide (VH2O2) biological indicators (BIs) including necessary physical characteristics of the BI unit, BI types, proper BI placement, and challenges encountered.